Choline

  • Forms DNA and cell structures
  • Supports the central nervous system
  • Maintains 6 Step Liver Cleanse – Dr. Axe liver heath
  • Protects the brain
  • Improves physical performance and muscle-building
  • Promotes cardiovascular health
  • Promotes prenatal health
  • Ensures proper child development

Best Choline

#1 Real Supplements Rated Best in 2020
Choline Bitartrate 650 mg 200 Veggie Capsules ( Vegan, Non-GMO & Gluten-Free) Supports Healthy Cognitive Functions & Mental Focus*
  • Choline Bitartrate Powder With 650 mg per Serving (serving is 2 caps) Max Supply (200 Veggie Capsules & 100 Day Supply .Providing 267 mg of Elemental Choline per serving. Suitable for Vegan/Vegetarian diets, Non-GMO, Gluten-free and all natural formulation.
  • Supports Cognitive Function* Supports Cellular Function* Supports Healthy Metabolism*.
  • Manufactured in the USA in a cGMP registered facility with the highest standards.
  • As a small family business, we fully understand the uncertainty and risk of trying new supplements. And this is why we go extra mile to source only the highest quality ingredients. Also, trust and transparency is at the forefront of our brand. We list every single ingredient on our products so that you can make an informative decision. Let us know if you have any questions or if can be of any service!
  • We source ingredients exclusively from partners who share our rigor for quality, choosing ingredients that meet stringent requirements, such as: identity, purity, potency and bioavailability, so you can achieve the maximum benefits.
Sale#2 Real Supplements Rated Best in 2020
Horbaach Choline Inositol 1000 mg (200 Capsules) | Non-GMO, Gluten Free Supplement
385 Reviews
Horbaach Choline Inositol 1000 mg (200 Capsules) | Non-GMO, Gluten Free Supplement
  • Non-GMO; Free of Gluten, Wheat, Yeast, Milk, Lactose and Soy
  • Choline & Inositol 1000 mg 200 Capsules; Great bulk size
  • Supports nervous system and cognitive health*
  • Supports healthy liver function and fat metabolism*
  • Superior cellular health formula*
Sale#3 Real Supplements Rated Best in 2020
Solgar – Choline/Inositol 500 mg/500 mg, 100 Vegetable Capsules
  • B-COMPLEX MEMBERS: Both Choline and Inositol are members of the B Complex and components cell membranes that provide key support for optimal cellular function
  • COMBINED BENEFITS: Inositol and Choline promote normal, healthy nerve and brain function as well as provide support for energy metabolism
  • ADDED CHOLINE BENEFIT: Choline is involved in the chemistry of the brain where it is used to synthesize acetylcholine. Acetylcholine is a critical neurotransmitter that is required for healthy brain function
  • EXTRA SUPPORT: In addition to nerve and brain support, Choline/Inositol also supports liver health and it helps promote normal fat metabolism
  • KOSHER, GLUTEN FREE & SUITABLE FOR VEGETARIANS: These vegetable capsules are KOF-K Kosher certified, suitable for vegetarians and are certified gluten free. They are free of: gluten, wheat, dairy, soy, yeast, sugar, and sodium. They are also free of artificial flavors, sweeteners, preservatives and colors
#4 Real Supplements Rated Best in 2020
NOW Choline and Inositol 500mg, 100 Capsules (Pack of 2)
  • Choline is necessary for normal synaptic transmission and brain health and involved in fatty acid metabolism in the liver
  • Inositol is also essential for brain and nervous system health
  • Supports Healthy Nerve Transmission
  • Assists in Fatty Acid Metabolism
Sale#5 Real Supplements Rated Best in 2020
Solgar – Choline 350 mg, 100 Vegetable Capsules
  • WHAT IS CHOLINE: Choline is a member of the B Complex which is a component of cell membranes that provide key support to allow for cellular function at an optimal level
  • HOW IT WORKS: Choline is involved in the chemistry of the brain where it is used to synthesize acetylcholine. Acetylcholine is a critical neurotransmitter that is required for healthy brain function
  • ADDITIONAL SUPPORT: Choline is also known to provide support for the liver and it also has a role in promoting normal fat metabolism
  • KOSHER, GLUTEN FREE & SUITABLE FOR VEGETARIANS: These vegetable capsules are KOF-K Kosher certified, suitable for vegetarians and are certified gluten free. They are free of: gluten, wheat, dairy, soy, yeast, sugar, and sodium. They are also free of artificial flavors, sweeteners, preservatives and colors
#6 Real Supplements Rated Best in 2020
Standard Process - Choline - 90 Tablets
  • Supports healthy cell membrane structure and function
  • Provides support for methylation reactions
  • Supports healthy liver and gallbladder function
  • Supports a healthy nervous system
  • Standard Process: High-quality products that work the way nature intended
Sale#7 Real Supplements Rated Best in 2020
NOW Supplements, Choline & Inositol 500 mg, Healthy Nerve Transmission*, Nervous System Health*, 100 Capsules
  • SUPPORTS HEALTHY NERVE TRANSMISSION*: Choline is necessary for normal synaptic transmission, brain health, and fatty acid metabolism in the liver.*
  • ASSISTS IN FATTY ACID METABOLISM*: Inositol is also essential for brain and nervous system health.*
  • CERTIFICATIONS/CLASSIFICATIONS: Kosher, Non-GMO, Soy Free
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968.
#8 Real Supplements Rated Best in 2020
Alpha GPC Choline Supplement (Beginner Nootropic for Brain Support, Focus, Memory, Motivation, and Energy) Pharmaceutical Grade, Made in USA (60 Capsules 300mg)
  • PROMOTE CHOLINE LEVELS - Alpha GPC is a highly bioavailable form of Choline which helps support healthy Choline levels
  • SUPPORT YOUR MEMORY - Remember more information for your exams, forget less deadlines at work, no more losing your car keys
  • SUPPORT ACETYLCHOLINE SYNTHESIS- Nootropics supplement to support memory, focus, and acetylcholine levels
  • MADE IN THE USA - Our Alpha GPC is manufactured right here in the USA
  • SAFETY TESTED IN THE USA - Double Wood's Alpha GPC is safety tested for heavy metals and microbes in New York
#9 Real Supplements Rated Best in 2020
CDP Choline (Citicoline) Supplement, Pharmaceutical Grade, Made in USA (60 Capsules 300mg)
  • INCREASE CHOLINE LEVELS - CDP Choline is an effective and potent Choline source.
  • ENHANCE MEMORY - Retain more of what you learn, and recall memories with greater ease.
  • BOOST COGNITIVE FUNCTION - Improves working memory, focus, and mental energy
  • MADE IN THE USA - Our CDP Choline is manufactured right here in the USA
#10 Real Supplements Rated Best in 2020
Phosphatidylcholine 1,200mg – 210 Softgels – Enhanced Version of Sunflower and Soy Lecithin - Non-GMO, Made and Tested in the USA to Support Brain Health by Double Wood Supplements
  • MADE IN THE USA AND TESTED FOR PURITY – Our Phosphatidyl Choline (PC) soft gels are manufactured right here in New York. Testing is available upon request.
  • SUPPORTS COGNITIVE FUNCTION – Studies have shown that PhosphatidylCholine may help enhance memory and overall cognitive function by increasing levels of choline and acetylcholine in the brain.
  • SUPPORT THE AGING BRAIN – Low levels of Phosphadtylcholine (PCC) have been linked to decreased cognitive function and impaired mental abilities, especially as one ages.
  • PROMOTES LIVER HEALTH – Low levels of Phosphatidylcholine are linked to poor liver function and increased PC may promote liver regeneration.
#11 Real Supplements Rated Best in 2020
Nature's Way Choline, 500 mg, 100 Tablets, Pack of 2
  • Choline is the precursor for the neurotransmitter acetylcholine and is involved in healthy brain function*
  • It is essential for normal function of all cells.*
  • Vegetarian and gluten-free formula
  • Contains no salt, soy, wheat, yeast-derived ingredients, gluten, preservatives, dairy products, artificial flavors or preservatives
#12 Real Supplements Rated Best in 2020
High Quality Choline - 500 mg - 120 Veggie Capsules - by Doctor Recommended Supplements - Supports Cognitive Health, Memory & More
  • BRAIN FUNCTION – Choline is necessary for proper mental function and can help delay memory loss and absentmindedness. Our supplement is formulated with only the highest-quality Choline to improve focus and alertness.*
  • DELAY FATIGUE – Help your body meet the demands of intense training. Athletes favor Choline to keep fatigue from slowing them down in the middle of training or performance and to assist muscle building and recovery for bodybuilders.*
  • DIETARY STANDARDS – Doctor Recommended Choline Supplements are a vegan-friendly and gluten-free way to support cellular health and mental sharpness. They are manufactured according to Halal standards and are also Kosher.*
  • SUPPORT METABOLISM – Choline is naturally occurring in foods like liver and shrimp, and the body makes some, but most of us don’t get enough in our diets. Our Choline provides the amount needed to keep your body’s systems running well.*
  • MADE IN THE USA – We want you to feel great about the safety and quality of your health and wellness supplements. We manufacture all of our health products in the USA lab so that you can feel confident taking them every day.
#13 Real Supplements Rated Best in 2020
Pure Synergy Choline Complex (60 Tablets) Choline Vitamin Made with Organic Veggies & Sprouts
  • Made with organic vegetables and sprouts, and fermented so it’s absorbed just like food
  • Promotes healthy cognitive function & supports brain & nervous system health
  • Supports healthy liver function as well as healthy bile & fat metabolism
  • Important for healthy prenatal brain development
  • Made with Organic Ingredients, Non-GMO, Gluten-Free, Vegan, Dairy-Free
#14 Real Supplements Rated Best in 2020
Best Naturals Choline Bitartrate 650 mg (Non-GMO) for Healthy Cognitive Brain Function 180 Tablets
  • 100% MONEY BACK GUARANTEE – Try the Best - Risk Free! These Choline Supplement and covered by a no-questions asked money back guarantee.
  • Best Naturals Choline made with Non-GMO Choline which Supports mental acuity & energy, Supports healthy metabolism, Promotes cellular function, Supports nerve & liver health*
  • THE MOST BIO-AVAILABLE FORM OF CHOLINE - Best Naturals Choline contains a highly bioavailable form of choline that is easily absorb into body and give real effect.*
  • No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Lactose, No Gluten, No Wheat, No Yeast, No Fish, No Sodium.
  • All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency Guaranteed
#15 Real Supplements Rated Best in 2020
Choline & Inositol 1000mg 200 Veggie Caps (100% Vegetarian, Non-GMO & Gluten Free) Brain Health Supplement - All Natural Ingredients - Promotes Healthy Brain & Nerve Function
  • ✅✅✅SUPPORTS NERVOUS SYSTEM HEALTH: Choline & Inositol are essential for brain health and work together to help relax and improve nervous system health.*
  • ✅✅✅PROMOTES HEALTHY BRAIN FUNCTION: Both Choline & Inositol keep anxiety and stress in check by promoting normal synaptic transmission for healthy brain function*
  • ✅✅✅SUPPORTS ENERGY: These all natural essential nutrients deliver necessary components that fight off fatigue, depression, and stress to help keep you focused and alert.*
  • ✅✅✅MANUFACTURED IN USA: Produced by GMP facilities with the highest manufacturing and sourcing standards of NusaPure.
  • ✅✅✅STILL NOT SURE? DON’T WORRY! – As a small family business, we fully understand the uncertainty and risk of trying new supplements. And this is why we go extra mile to source only the highest quality ingredients. Also, trust and transparency is at the forefront of our brand. We list every single ingredient on our products so that you can make an informative decision. Let us know if you have any questions or if can be of any service!
#16 Real Supplements Rated Best in 2020
Bulksupplements Choline L-Bitartrate Powder (250 Grams)
  • Boosts athletic endurance and Assists in muscle recovery*
  • Promotes heart health and Helps support the liver*
  • Aids in maintaining healthy weight*
  • Supports memory & brain function*
  • Contributes to overall health & wellness*
#17 Real Supplements Rated Best in 2020
Amazing Formulas Choline Bitartrate - 650 MG, 180 Tablets (Non-GMO,Gluten Free) – Supports Nerve & Brain Health - Promotes Cellular Function - Cognitive Support
  • SUPPORT HEALTHY BRAIN FUNCTION Amazing Nutrition Choline dietary supplement support brain health, provides cognitive support for concentration and learning and promotes healthy nervous system cells
  • THE BEST FORM OF CHOLINE Our supplement contains a highly bioavailable form of choline that is easy for thebody to process
  • SIMPLE TO ADD TO YOUR DIET Just one of our choline tablets provides 650 milligrams of choline bitartrate making supplementation easy
  • All Amazing Formulas products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world.
  • All our products are proudly made in USA with Guaranteed Purity & Potency. We offer best quality products for the best value. All our products are Third Party Tested. We do not compromise on quality
#18 Real Supplements Rated Best in 2020
Nature's Way Choline and Inositol, 1,000 mg per serving, 100 Capsules
  • BRAIN HEALTH & CELLULAR ENERGY.* With 1,000 mg choline and inositol per serving.
  • RESPONSIBLE PACKAGING. Bottle made with 97% post-consumer recycled materials. Please recycle.
  • GLUTEN-FREE. No sugar, salt, yeast-derived ingredients, wheat, dairy, or artificial colors, flavors, or preservatives.
Sale#19 Real Supplements Rated Best in 2020
Citicoline CDP Choline 500mg | 60 Capsules | Highest Potency Per Capsule | Non-GMO, Gluten Free Supplement | by Carlyle
  • Non-GMO; Free of Gluten, Wheat, Milk, Lactose and Soy
  • Each capsule in our 60 Capsule bottle of Citicoline CDP Choline Supplement contains 500 mg
  • This extra strength CDP Choline supplement delivers 1000 mg per serving
  • Pills from CDP-Choline bulk powder (citicoline sodium); citicoline is a known B-Vitamin
  • Citicoline is a naturally-occuring chemical that supports healthy cognitive brain function*
#20 Real Supplements Rated Best in 2020
Now Foods Choline & Inositol 500 Mg - 100 Caps
  • Nervous System Health
  • Supports Healthy Nerve Transmission
  • Assists in Fatty Acid Metabolism
  • A Dietary Supplement
  • Vitamins

Best 8 Benefits of Choline

Choline is a water-soluble micronutrient that has many benefits. It promotes the structural integrity of cells and enables them to send out signals throughout the body. Choline also supports several processes, including metabolism, DNA replication, brain development, muscle movement, and liver function, as well as increases energy. Choline also aids in the production of numerous hormones and chemicals such as acetylcholine (a neurotransmitter) and found in body fat.

Choline can be found naturally in many foods, including eggs, beef, salmon, liver, and cauliflower. Your body also produces choline, and it is thought that increased intake of folate leads to greater choline production. A deficiency in choline can cause problems with the nervous, endocrine, digestive, and reproductive systems.

Let’s take a closer look at some of the benefits of choline.

1. Forms DNA and cell structures

Choline aids the body in fat absorption, which is then used to create cell structures such as the cell membrane. Without choline, cells cannot hold their structure and transmit signals to other cells. This micronutrient is also needed to create DNA. Paired with folate, choline helps produce methyl groups, which the body them uses to form genetic material.

2. Supports the central nervous system

The central nervous system is comprised of the brain and the spinal cord. Choline aids in the formation of neurotransmitters like acetylcholine, which is used to help various nerves and muscles function. One specific function choline plays a part in is signaling; it allows nerves to transmit signals across the body quickly and accurately, and it also helps protect neuronal membranes from damage. Acetylcholine in particular plays a role in memory and learning, so a choline deficiency can lead to poor memory, lack of concentration, mood swings, and other cognitive impairments, particularly in old age.

3. Maintains 6 Step Liver Cleanse – Dr. Axe liver heath

Choline is needed to transport fats such as cholesterol and triglycerides from the liver throughout the body and helps prevent the buildup of unhealthy fat in the liver. It is also responsible for producing LDL cholesterol. Though too much LDL cholesterol is bad for your health, some is still needed; without it, the liver will store excess fat. Low levels of choline have also been associated with higher risk of liver damage and even failure.

4. Protects the brain

Another benefit of choline is its restorative power for the brain. Because of its role in building cell membranes and neurotransmitters, it helps preserve neurons, thus maintaining memory and preventing dementia and other forms of mental decline. Brain elasticity, like acetylcholine, naturally declines with age, but increased intake of choline helps the brain retain its elasticity and produce enough acetylcholine to maintain proper function. In fact, some studies have suggested that low acetylcholine levels may lead to cognitive impairments such as Alzheimer’s 11; some medications used to treat Alzheimer’s actually mimic the effect of choline on the nervous system.

5. Improves physical performance and muscle-building

Choline aids in focus and concentration, improves mental energy and ability, and quickens mental processing and reaction times. In addition to improving mental stamina, choline enhances physical aspects as well, such as physical energy, sleep cycles, and recovery time after strenuous activity. It has also been shown to prevent fatigue and relieve muscle aches.

6. Promotes cardiovascular health

Along with folate, choline helps convert the amino acid homocysteine; this prevents the body from accumulating too much fat and can reduce the risk of heart attack and stroke. When coupled with lecithin, choline also reduces the risk of heart disease. Research also suggests that this combination may also reduce triglycerides and LDL cholesterol, but further study is needed.

7. Promotes prenatal health

Choline is consumed rapidly by a developing fetus, which uses the nutrient in the development of the brain, nerve channels, and cell structures. Some studies even suggest that increased fetal consumption of choline can produce a sharper mind and reduce the risk of cognitive abnormalities, whereas a choline deficiency can lead to neural tube defects and other developmental problems. This nutrient is found naturally in breast milk and is frequently added to infant formulas so the infant’s nervous system can develop properly. Choline, folate, and other B vitamins all work together. If a fetus is deficient in the latter two nutrients, choline, a methyl donor, can help fill in until proper amounts of those minerals are obtained.

8. Ensures proper child development

Neuroplasticity, the brain’s ability to form and maintain new neural connections, is greatly benefited by choline. Developing children naturally have plastic brains, meaning their brains are extremely malleable when it comes to learning new skills, thinking logically, and concentration. Choline is essential for healthy neurotransmitters in children. When children receive sufficient amounts of choline, their concentration, mathematical skills, social skills, creative thinking, and retention are improved. Some research even suggests that choline can prevent learning and behavioral disabilities such as ADHD.


Real Supplements gives you the best Choline on the market today. Our top-rated lists are fresh and current so you get the best options.

Real Supps Team

We needed to put together a site we could send our friends and clients to with confidence they were getting the most updated information.  We hope this site is used as a reference that will make your purchase easier and with as much knowledge as we can share.

With over 30 years experience in the health and fitness industry, we are a team of fitness bloggers and entrepreneurs, certified personal trainers and nutritionists contributing to bringing the most up-to-date content.  We send our friends and clients here for reference to new supplements and hope it serves as a reference site for you as well.

Amazon Best Rated Products - Last Updated on 2020-09-19.

DISCLAIMER: There are affiliate links on this page. This means that at no cost to you, we will receive a small commission if you purchase through our link.